A compound, its use, a medicament, a pharmaceutical composition, a method for preventing or treating a disease against which gene expression control is effective, a method for preventing or treating a disease for which suppression of vegf production is effective, and a method. to prevent or treat a disease against which an inhibition of angiogenesis is effective

摘要

"COMPOSITION, ITS USE, MEDICINAL PRODUCT, PHARMACEUTICAL COMPOSITION, METHOD TO PREVENT OR TREATMENT OF A DISEASE WHICH A GENE EXPRESSION CONTROL IS EFFECTIVE, METHOD TO PREVENT OR TREATMENT A DISEASE, WHICH THE SUPPRESSION OF EFFECTIVE PRODUCTION IS METHOD FOR PREVENTING OR TREATING A DISEASE AGAINST AN ANGIOGENESIS INHIBITION ". The present invention relates to a compound represented by the formula (I): (wherein, R 3, R 6, R 7 and R 21 are the same or different from each other and each represents a group. hydroxyl, etc.), a pharmacologically acceptable salt thereof or a hydrate thereof. The compound of formula (I) of the present invention suppresses angiogenesis, in particular, suppresses VEGF production in a hypoxic condition and is useful as a therapeutic agent for treating solid cancer.