首页> 外国专利> Chemical compound, pharmaceutical composition, methods for synthesizing a chemical compound, for treating ischemia-reperfusion damage, liver disease, arrhythmia and cancerous and precancerous cell (s), to increase expression of connexin 43 is a disease with a chemical composition comprising a carotenoid derivative and for reducing a c-reactive protein.

Chemical compound, pharmaceutical composition, methods for synthesizing a chemical compound, for treating ischemia-reperfusion damage, liver disease, arrhythmia and cancerous and precancerous cell (s), to increase expression of connexin 43 is a disease with a chemical composition comprising a carotenoid derivative and for reducing a c-reactive protein.

机译:化合物,药物组合物,用于治疗缺血-再灌注损伤,肝病,心律不齐以及癌细胞和癌前细胞的合成化合物的方法,以增加连接蛋白的表达43是一种具有包含类胡萝卜素衍生物的化学组成的疾病并用于减少c反应蛋白。

摘要

"CHEMICAL COMPOUND, PHARMACEUTICAL COMPOSITION, METHODS TO SYNTHESIZE CHEMICAL COMPOUND, TO TREAT ISCHEMIA-REPERFUSION DAMAGE, ARRYTHMIA AND SUGAR CANCER (S) CANCER (S) CELLS 43 AND A DISEASE WITH A CHEMICAL COMPOSITION UNDERSTANDING A CAROTENOID DERIVATIVE AND TO REDUCE A C-REACTIVE PROTEIN ". Method for inhibiting and / or improving the occurrence of diseases associated with reactive oxygen species reactive, radical and / or non-radical nitrogen species in an individual, thus an individual is administered with a carotenoid structural analog, either alone or in combination with another carotenoid analog, or co-antioxidant formulation. The analog or combination of analogs is administered such that the individual's risk of experiencing diseases associated with reactive oxygen species, reactive nitrogen species, radicals and / or non-radicals can thus be reduced. The analog or combination of analogs may be administered to an individual for the inhibition and / or amelioration of ischemia-reperfusion damage. The analog or combination of analogs may be administered to an individual for inhibiting and / or ameliorating liver disease. The analog or combination of analogs may be administered to an individual for inhibition and / or amelioration of cancer. The analog or combination of analogs may be administered to an individual for inhibiting and / or ameliorating cardiac arrhythmia and / or sudden cardiac death. The analog or combination of analogs may be administered to an individual for the inhibition and / or amelioration of any disease involving the production of reactive oxygen species, reactive nitrogen species, radicals and / or non-radicals. In one embodiment, a water-soluble and / or water-dispersible astaxanthin analog is particularly effective. This invention further includes pharmaceutical compositions comprising structural carotenoid analogs either alone or in combination.
机译:“化学化合物,药物成分,化学成分的合成,缺血再灌注损伤,前庭和糖癌细胞43的治疗以及具有化学成分的疾病,这些疾病取决于心血管和心血管疾病反应蛋白”。抑制和/或改善个体中与活性氧,自由基和/或非自由基型氮有关的疾病发生的方法,因此单独或与另一种类胡萝卜素联合给予类胡萝卜素结构类似物类似或共抗氧化剂配方。施用类似物或类似物的组合,从而可以降低个体患与活性氧,活性氮,自由基和/或非自由基有关的疾病的风险。可以将类似物或类似物的组合施用于个体以抑制和/或改善缺血-再灌注损伤。可以将类似物或类似物的组合给予个体以抑制和/或改善肝病。可以将类似物或类似物的组合施用于个体以抑制和/或改善癌症。可以将类似物或类似物的组合施用于个体以抑制和/或改善心律不齐和/或心源性猝死。可将类似物或类似物的组合施用于个体,以抑制和/或改善涉及产生活性氧,活性氮,自由基和/或非自由基的任何疾病。在一个实施方案中,水溶性和/或水分散性虾青素类似物特别有效。本发明还包括单独或组合包含结构类胡萝卜素类似物的药物组合物。

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