Methods for regulating hematocrit level in humans, for preparing an erythropoietin product, and for treating anemia in patients at risk of tissue injury, man-made erythropoietin product, and pharmaceutical composition

摘要

"METHODS TO REGULATE HEMATOCYTE LEVEL IN HUMANS, TO PREPARE AN ERYTHROPOIETIN PRODUCT, AND, TO TREAT ANEMIA IN TISSUE INJURY PATIENTS, EYTHROPYETIN PRODUCED BY HEMEM, AND COMPOSITE METHODS an individual while maintaining endogenous tissue protective activities by administering a chemically modified long-lasting erythropoietin-containing pharmaceutical compound. Also disclosed are novel chemically modified long-term erythropoietins, methods of producing chemically modified long-term erythropoietins, and compositions comprising chemically modified long-term erythropoietins.