IDENTIFICATION OF SPECIFIC TUMOUR ANTIGENS BY MEANS OF THE SELECTION OF CDNA LIBRARIES WITH SERA AND THE USE OF SAID ANTIGENS IN DIAGNOSTIC IMAGING TECHNIQUES

摘要

A method is described for the identification of specific tumour antigens by means of the selection of cDNA libraries with sera, characterised in that said selection is accomplished with the phage display technique, and in particular said selection is accomplished by means of the SEREX technique (serological analysis of autologous tumour antigens through the expression of recombinant cDNA). The method according to the invention described herein advantageously combines the SEREX approach with the potency of the phage display technique defined above, at the same time avoiding the drawbacks characteristic of the SEREX technique.