USE OF BLOCKERS OF THE LONG TERM INHIBITION OF THE ACTIVITIES OF ATPASE NA + K + E / OR OF THE NA + / H + EXCHANGE, IN THE PREPARATION OF A MEDICATION INTENDED FOR THE THERAPYTESTINAL

摘要

The present invention relates to the use of blockers for the long-term inhibition of Na+-K+-ATPase and/or Na+/H+ exchange activities that act at the level of enzymatic activity inhibition, for the preparation of medicament for the prevention and treatment of changes in intestinal electrolyte absorption associated with inflammatory bowel disease in mammals. The invention is also concerned with a pharmaceutical composition comprising a therapeutically effective amount of the said blocker in combination with a pharmaceutically acceptable carrier.