5- (2- 4- (1,2-BENZISOYZAZOL-3-YL) -1-PIPERAZINYL -6-CHLORO-1,3-DIHYDRO-2 (1H) -INDOL -2-ONA (= ZIPRASIDONE), ITS PREPARATION AND ITS USE AS DOPAMINE D2 ANTAGONISTS

摘要

The invention is directed to the mesylate dihydrate salts of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one, pharmaceutical compositions containing said ziprasidone mesylate dihydrates, and methods of adminsitering the ziprasidone mesylate dihydrates to treat psychotic diseases.