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Treatment of arthritis and compositions therefore containing a n-acylated-2-glucosamine derivative
Treatment of arthritis and compositions therefore containing a n-acylated-2-glucosamine derivative
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机译:治疗关节炎及其因此包含n-酰化-2-葡萄糖胺衍生物的组合物
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摘要
A 2-glucosamine derivative of the general formula (I):wherein R is an alkyl radical of the general formula CnH2n+1 and n is selected from 2-12; and pharmaceutically acceptable salts, esters and glucosides thereof, used for a treatment in a mammal selected from the group consisting of (a) arthritis, particularly osteoarthritis and inflammatory arthritis; (b) enhancing cartilage formation in a mammal; (c) enhancing chondrocytes cell proliferation; (d) production of glycosaminoglycan in a mammal; and (e) alleviating the symptoms of joint stiffness and restricted mobility.
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