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Pharmaceutical preparations of bioactive substances extracted from natural sources

机译:从天然来源提取的生物活性物质的药物制剂

摘要

This invention relates to methods of extracting and purifying bioactive substances from various plants and herbs. More specifically the invention relates to methods of extracting and separating bioactive substances from various plants and herbs, such as Kava root, Byrsonima species, Aesculus californica, Crataegus mexicana, Simmondsia chinensis, Pfaffia species, Alternanthera repens, Bursera species, Turnera species, Perezia species, Heimia salicifolia, Psidium species, Enterlobium species, Ptychopetalum olacoides, Liriosma ovata, and Chaunochiton kappleri, using supercritical fluid extraction and/or fluorocarbon solvent extract. The present invention further relates to separation of bioactive substances contained in extracts using packed column supercritical fluid chromatography or HPLC where dense gas with or without modifiers is the mobile phase. The present invention also relates to pharmaceutical preparations and dietary supplements which may be prepared with the extracted bioactive substances and use of such pharmaceutical preparations and dietary supplements to treat various human aliments.
机译:本发明涉及从各种植物和草药中提取和纯化生物活性物质的方法。更具体地,本发明涉及从各种植物和草药中提取和分离生物活性物质的方法,所述植物和草药诸如卡瓦根,拜氏菌属,加州七叶树,墨西哥山楂,西蒙蒙德斯,Pfaffia种,Alternanthera repens,布尔氏菌属,Turnera属,Perezia属。 ,Heimia salicifolia,Piddium物种,Enterlobium物种,Ptychopetalum olacoides,Loriosma ovata和Chaunochiton kappleri,使用超临界流体萃取和/或碳氟化合物溶剂萃取。本发明进一步涉及使用填充柱超临界流体色谱法或HPLC分离提取物中所含的生物活性物质,其中具有或不具有改性剂的浓气体为流动相。本发明还涉及可以与提取的生物活性物质一起制备的药物制剂和膳食补充剂,以及这种药物制剂和膳食补充剂在治疗各种人类饮食中的用途。

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