siRNA EXPRESSION SYSTEM AND METHOD FOR PRODUCING FUNCTIONAL GENE KNOCK-DOWN CELLS USING THE SYSTEM

摘要

An in vivo siRNA expression system whereby an si(small interfering)RNA is expressed in cells. This system has an antisense code DNA encoding an antisense RNA to a domain of a target gene mRNA, a sense code DNA encoding a sense RNA in a domain of the target gene mRNA, and one or more promoters for expressing the above-described antisense RNA and the above-described sense RNA by the above-described antisense code DNA and the above-described sense code DNA.