DETERMINATION OF GENETIC VARIANTS IN A POPULATION USING DNA POOLS

摘要

The invention provides a system and methods for detecting genetic variants including resistance or genetic susceptibility to disease in a population of individuals using pooled DNA to identify the presence of the desired variant at a genetic locus or loci. In particular, the present invention provides a method for rapidly and relatively inexpensively eliminating from the screening process groups of individuals that lack the gene variant of interest.