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MULTICELLULAR ORGANISMS DERIVED FROM NORMAL/NONDISEASED AND DISEASED MAMMALIAN TISSUES

机译:正常/未患及患哺乳动物组织的多细胞有机体

摘要

The present invention relates to pleomorphic cells ('morphotes'), which exhibit morphologic and genetic characteristics of both prokaryotic and eukaryotic cells, including resemblance to prokaryotic cells at the unicellular level, and resemblance to eukaryotic cells at the multicellular level due to their ability to self-organize in vitro into multicellular, mammalian tissue-like patterns consisting of tissue-like sheets, capillary-like networks, and trabecular (spongy) bone-like structures. Morphotes have a number of applications in the diagnostic medical, therapeutic medical, biological, biomaterials, bionanotechnological, and industrial fields.
机译:本发明涉及多形细胞('morphotes'),其表现出原核和真核细胞的形态和遗传特征,包括在单细胞水平上类似于原核细胞,并且由于它们的能力而在多细胞水平上类似于真核细胞。在体外自我组织成多细胞,哺乳动物组织样模式,该模式由组织样片,毛细管样网络和小梁(海绵状)骨样结构组成。形态素在诊断医学,治疗医学,生物,生物材料,生物技术和工业领域中具有许多应用。

著录项

  • 公开/公告号WO2005090554A1

    专利类型

  • 公开/公告日2005-09-29

    原文格式PDF

  • 申请/专利权人 DENOVO BIOLOGIC LLC;ROBINSON DOUGLAS H.;

    申请/专利号WO2005US08920

  • 发明设计人 ROBINSON DOUGLAS H.;

    申请日2005-03-17

  • 分类号C12N1/20;C12N1/21;C12Q1/02;C12Q1/68;A61K35/74;C02F3/00;

  • 国家 WO

  • 入库时间 2022-08-21 22:08:36

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