首页> 外国专利> Lancifolide derivatives isolated from Actinodaphne lancifolide and composition containing the same showing anticancer activity

Lancifolide derivatives isolated from Actinodaphne lancifolide and composition containing the same showing anticancer activity

机译:从放线菌素兰西佛利中分离出的兰西佛利衍生物及其组合物具有抗癌活性

摘要

The present invention relates to a composition comprising as a lactone compound, is when polite (lancifolide) derivative, and this active ingredient separated from the nearly tree having anticancer activity (Actinodaphne lancifolia), is when pawl fluoride derivatives of the present invention the rat the exhibits lung cancer cell lines (LLC) and human blood cancer cell lines (HL60, K562) inhibiting growth, and Lewis lung carcinoma in mice body growth (Lewis lung carcinoma, LLC) cells, inhibition of various cancers, especially for the prevention and treatment of solid tumors or blood cancers such as lung cancer it can be used as an effective drug.
机译:本发明涉及一种组合物,其包含作为内酯化合物的礼貌(lancifolide)衍生物,并且该活性成分与具有抗癌活性的近树(Actinodaphne lancifolia)分离,是当本发明的棘爪氟化物衍生物用于大鼠时。表现出抑制生长的肺癌细胞系(LLC)和人血癌细胞系(HL60,K562),以及小鼠体内生长的Lewis肺癌细胞(Lewis肺癌,LLC),抑制各种癌症,特别是用于预防和治疗对于实体瘤或血液癌症(例如肺癌),它可以用作有效药物。

著录项

  • 公开/公告号KR100512316B1

    专利类型

  • 公开/公告日2005-09-02

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20050065939

  • 申请日2005-07-20

  • 分类号A61K31/365;

  • 国家 KR

  • 入库时间 2022-08-21 22:03:28

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