Bacteria with an increased protein secretion, nucleotide sequences encoding a protein seca with increased protein secretion, as well as a process for the production of proteins

摘要

The present invention relates to bacteria, which as a result of genetic modification of an increased secretion for proteins, as well as gene structures nucleotide sequences, which contain at least one gene encoding a protein seca with increased secretion for proteins encoded, a seca with an increased protein secretion, as well as a process for the production of desired proteins using the novel bacteria.The subject matter of the invention are nucleic acids encoding a protein seca with increased secretion for proteins, containing a gene sequence seca or an allele, homologous or derivative of these nucleotide sequences or nucleotide sequences hybridizing with the latter, which have at least one mutation. It has surprisingly been determined that a mutation in a nucleotide of the gene seca to an increased secretion for proteins and / or to a first time possible secretion of proteins leads.