A lactic acid strain named Pediococcus pentosaceus CBT-8 that produces an antibacterial active substance that suppresses the growth of Helicobacter pylori and Listeria monocytogenes, an antibacterial property using the same Method for producing antibacterial substance and method for using antibacterial substance for live bacteria in functional foods and pharmaceuticals

摘要

PURPOSE: A microorganism Pediococcus pentosaceus CBT-8 producing antimicrobial materials inhibiting growth of Helicobacter pylori and Listeria monocytogenes, and a method for producing the same, as well as the use thereof are provided, thereby preventing and treating infection of Helicobacter pylori and Listeria monocytogenes. CONSTITUTION: A microorganism Pediococcus pentosaceus CBT-8(KCTC 10297BP) produces antimicrobial materials inhibiting growth of Helicobacter pylori and Listeria monocytogenes. A method for producing antimicrobial materials comprises the steps of: (a) preparing Pediococcus pentosaceus CBT-8(KCTC 10297BP); (b) mixing 3 to 5 wt.% of glucose, 0.5 to 1 wt.% of yeast extract, 1 to 1.5 wt.% of meat extract, 0.5 to 1 wt.% of protein hydrolysate, and 0.01 to 0.1 wt.% of one or more compound selected from ammonium citrate, sodium acetate, dipotassium phosphate, magnesium sulfate, manganese sulfate, and sodium chloride; (c) sterilizing the mixture; and (d) inoculating Pediococcus pentosaceus CBT-8(KCTC 10297BP) to the medium and anaerobically fermenting it.