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Metastasis suppressor gene on human chromosome 8 and its use in the diagnosis, prognosis and treatment of cancer

机译:人类8号染色体上的转移抑制基因及其在癌症的诊断,预后和治疗中的应用

摘要

The invention provides an isolated or purified ribonucleic acid (RNA) molecule comprising a nucleotide sequence encoded by a human (Tey1) metastasis suppressor gene located at p21-p12 on chromosome 8 or a fragment thereof, wherein the isolated or purified RNA molecule comprises from about 10 to about 100 nucleotides. The invention also provides methods of diagnosis, prognosis, and treatment of cancer, such as prostate cancer, using the isolated or purified RNA molecule.
机译:本发明提供了一种分离的或纯化的核糖核酸(RNA)分子,其包含由位于8号染色体上的p21-p12的人(Tey1)转移抑制基因编码的核苷酸序列或其片段,其中所述分离的或纯化的RNA分子包含约1-10%的RNA。 10至约100个核苷酸。本发明还提供了使用分离的或纯化的RNA分子诊断,预后和治疗诸如前列腺癌的方法。

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