Aryl - and heteroarilpiperidincarboxilatos Derivatives, their Preparation and their application in Therapeutics

摘要

The compound responds to the general formula (1),where m, n = 1, a 3 and m + n = 2 to 5; p = 1 to 7; A = single bond or X, Y and / or Z; X = optionally substituted methylene, Y = optionally substituted C2-alkylene or C2-alkylene; Z = C3-7 cycloalkyl, R1 represents a group of the aryl or heteroaryl type; R2 represents a hydrogen or fluorine atom, a hydroxyl group, C1-6 alkoxy or NR8R9; R3 represents a hydrogen atom or a C1-6 alkyl group; R4 represents a hydrogen atom or a C1-C6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-3alkyl group; in the base state, from the addition salt of an acid, hydrate or solvate. Therapeutic application.