heterologous fusion protein, polynucleotide, vector, host cell, process for producing a heterologous fusion protein, method for treating a patient, and use of heterologous fusion protein

摘要

"HYPEROLOGICAL FUSION PROTEIN, POLYNUCLEOTIDE, VECTOR, HOST CELL, PROCESS TO PRODUCE A HETEROLOGICAL FUSION PROTEIN, METHOD TO TREAT A PATIENT, AND, USE OF HYPERLOGUE PROTEIN." The invention provides active therapeutic peptides fused to specific IgG4-Fc derivatives. These fusion proteins have an increased half-life, reduced antibody medium formation, and reduced effector activity while being non-immunogenic. Fusion proteins are useful in treating diseases as well as a variety of other conditions and disorders.