composition of matter for immune response modulation in a subject antigen subject and its modulation method, antigen presenting cell production process and method of treatment and / or prophylaxis of disease or condition associated with the presence of target antigen of interest

摘要

"COMPOSITION OF MATTERS FOR IMMUNE RESPONSE MODULATION IN A SUBJECT TO A TARGET ANTIGEN AND THEIR MODULATION METHOD, ANTIGEN PRESENTATION CELL PROCESSING AND METHOD OF ANTIGES OR PRESENTATION OF THE INTERNAL PRESENTATION AND METHOD " The present invention relates to the use of at least one set of peptides in compositions and methods of modulating the immune response to one or more polypeptide antigens. In certain embodiments, sequences of a respective set of peptides are derived in whole or in part from a single polypeptide antigen. Individual peptides of a respective set of peptides comprise different parts of an amino acid sequence corresponding to a single polypeptide antigen and exhibit partial identity or sequence similarity to at least one other peptide of the same peptide set. The invention also extends to methods of using such peptides in a range of preventative, diagnostic and therapeutic applications. Additionally, the invention relates to the use of uncultivated antigen presenting cells or their precursors, which have not been subjected to activation conditions and which have been contacted with an antigen, in methods and compositions of formulating the immune response in a recipient. of those cells.