Method for culturing microorganisms having a methanol metabolic pathway.

摘要

The present invention describes a method of culturing microorganisms having a metabolic methanol utilization VIA, IN WHICH INTRODUCE an expression unit, comprising a gene DIANA, UNIDO DOWNSTREAM with respect to a promoter that can be induced by METHANOL . DURING THE CROP, and including the period during which PERIODICALLY add methanol, the addition rate FITS SPEED EQUAL TO OR LESS THAN THE MAXIMUM SPEED OF ETHANOL CONSUMPTION said microorganisms.