NOVEL 3-D POLYMER SCAFFOLD FOR TISSUE REGENERATION AND PREPARATION METHOD THEREOF

摘要

New 3D polymeric support structure for tissue regeneration, the porous structure of which is the inverse or "negative" of a three-dimensional porogen or "template" resulting from the sintering of overlapping nylon fiber meshes, characterized by a regular orthogonal network (figure 3) Cylindrical pores and channels of uniform size and clean of residual porogen, aligned and interconnected with each other, with a variable porosity above 75%, and with a pore and channel diameter also variable, in order of magnitude μ m . This new polymeric support structure, which is obtained by infiltration and polymerization in the template of the crosslinking material, elimination of the porogen by leaching and final drying of the resulting porous matrix, is chemically and mechanically stable, finding special application in regeneration or repair of human or animal tissues. (Machine-translation by Google Translate, not legally binding)