首页> 外国专利> NIACIN USED AS ORAL SUPPLEMENTATION FOR THE TREATMENT OF PSYCHOSIS AND/OR SCHIZOPHRENIA IN HUMANS

NIACIN USED AS ORAL SUPPLEMENTATION FOR THE TREATMENT OF PSYCHOSIS AND/OR SCHIZOPHRENIA IN HUMANS

机译:烟酸用作口服补品,用于治疗人类的精神分裂症和/或精神分裂症

摘要

The present invention addresses a vitamin and a method for amelioratingpsychoticand schizophrenic mental states that originate from biochemical imbalance.Braindisturbances such as paranoia, delusions, and hallucinations can result from asystemicNAD-deficiency. Additionally, impairments in prostaglandin mechanisms and/orbloodcirculation can have damaging repercussions on brain chemistry. A combinationof oralflush niacin, supplemented with sustained-release niacin, is employed in asuggestedhigh-dose regime. The immediate-release form of nicotinic acid initiates aprostaglandin-mediated surge of blood flow primarily to the truncal and facialsubcutaneous vessels. Patients also experience a benzodiazepine-like effectfrom theflush niacin, which is capable of quickly crossing the blood-brain barrier.Anxiety andagitation are quelled within minutes of ingestion.
机译:本发明涉及一种维生素及其改善方法精神病的和生化失衡引起的精神分裂症的精神状态。脑诸如偏执狂,妄想和幻觉之类的障碍可能是由系统的NAD缺乏。此外,前列腺素机制和/或受损血液血液循环可能会对脑部化学产生有害的影响。组合口头补充有缓释烟酸的冲洗烟酸用于建议的高剂量方案。烟酸的立即释放形式引发前列腺素介导的血流主要流向截骨和面部皮下血管。患者还会经历苯二氮卓类药物的作用来自冲洗烟酸,它能够快速穿过血脑屏障。焦虑和摄入后几分钟内即可消除躁动。

著录项

  • 公开/公告号CA2505808A1

    专利类型

  • 公开/公告日2006-11-02

    原文格式PDF

  • 申请/专利权人 GLOBUS JULIE DANIELLE;

    申请/专利号CA20052505808

  • 发明设计人 GLOBUS JULIE DANIELLE;

    申请日2005-05-02

  • 分类号A61K31/455;A61P25/18;

  • 国家 CA

  • 入库时间 2022-08-21 21:35:25

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