METHODS OF USE FOR SECRETED FRIZZLED-RELATED PROTEIN 3 (SFRP-3) IN THE PREVENTION AND TREATMENT OF DISEASE

摘要

Compositions containing sFRP-3 polypeptides, polynucleotides, and modulators thereof, such as antibodies thereto, are provided. Such compositions are useful for the treatment, prevention, and diagnosis of diseases. Such diseases include immune and proliferative diseases. Methods for utilizing these polypeptides, polynucleotides, and modulators aredisclosed; they include methods for treating proliferative, inflammatory, and bone and cartilage diseases.