METHOD OF SCREENING SAMPLE HAVING ANTIVIRAL ACTIVITY AGAINST VIRUS WITH ABILITY TO INFECT ORGANISM EXHIBITING ACQUIRED IMMUNE MECHANISM BY USE OF INDIVIDUAL ORGANISM, OR ITS CULTURED CELL, EXHIBITING NATURAL IMMUNE MECHANISM ONLY, AND METHOD OF ESTIMATING THE ANTIVIRAL ACTIVITY BY USE OF INDIVIDUAL ORGANISM, OR ITS CULTURED

摘要

Results have proved that infection deaths by nuclear polyhedrosis viruses of silkworm larvae can be remedied by ganciclovir, foscarnet, vidarabine and ribavirin used as therapeutic drugs for cytomegalus virus infection at human clinic. Findings indicate that the use of individual organism, or its cultured cell, exhibiting natural immune mechanism only, such as silkworm larva, leads to realization of screening of a sample having an antiviral activity against virus with ability to infect an organism exhibiting acquired immune mechanism, such as human, and realization of estimation of the antiviral activity.