SYNTHESIS OF ALPHA-AMINO-ALPHA',ALPHA'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF BETA)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME

摘要

The present invention provides a commercially profitable process for producing a β-amino acid ester derivativewhich comprises reacting an α-amino acid ester derivative with a base and a dihalomethane,reacting the same with a lithium amide and an alkyllithium in succession,and treating the reaction product with an acid in an alcohol.