ABIN-MEDIATED PROTECTION AGAINST LUNG INFLAMMATORY DISEASE

摘要

The present invention relates to the treatment of airway inflammation. Specifically, the airway inflammations which form the subject of the present invention are mediated by the transcription factor NF-κB. The treatment comprises the use of A20-binding inhibitors of NF-B activation (ABINs). The A20-binding inhibitors of NF-κB activation (ABINs) of the present invention are used in the preparation of a medicament for treating airway inflammation. The airway inflammations of the present invention include asthma and chronic obstructive pulmonary disease (COPD).