2,5-bis(tetrahydroxybutyl)pyrazines for the treatment of osteoarthritis and rheumatoid arthritis

摘要

Use in the prevention and/or in the treatment of Osteoarthritis and Rheumatoid Arthritis of 2,5-Bis(tetrahydroxybutyl)pyrazines, compounds of formula (I), is disclosed. Compounds of the invention act simultaneously on cartilage matrix degradation and on nitric oxide and prostaglandin E2 production.