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METHOD FOR PREDICTING 5 YEARS LONG SURVIVAL PERIOD WITHOUT PROGRESS IN THE CASES OF URINARY BLADDER CARCINOMA AFTER RADICAL SURGICAL TREATMENT
METHOD FOR PREDICTING 5 YEARS LONG SURVIVAL PERIOD WITHOUT PROGRESS IN THE CASES OF URINARY BLADDER CARCINOMA AFTER RADICAL SURGICAL TREATMENT
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机译:根治性手术后尿囊癌无进展的5年长期生存期预测方法
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FIELD: medicine.;SUBSTANCE: method involves determining invasion depth, cancer cell differentiation degree in neoplasm bioptate, staining the bioptate with silver nitrate solution, determining mean number of nucleoli Mn in 100 nuclei adjacent to each other and standard deviation of argentophilic granules in the nucleoli SDag. 5 years long survival without cancer progress at any invasion depth is calculated as S=2.289*Mn+0.219*SDag+0.998*pT-0.102*G, where pT is the urinary bladder carcinoma cell invasion depth (pTa=1, pT1=2, pT2=3, pT3=4, pT4=5); G is the urinary bladder carcinoma cell differentiation degree (G1=1, G2=2, G3=3). S values being ≤6.95, 5 years long survival without cancer progress is to be predicted. Nucleoli distribution variation coefficient CVn and argentophilic granules distribution excess Eag in nucleoli are additionally determined. The 5 years long survival without cancer progress Spr=0.1727*CVn+0.3276* Eag. Spr value being 7.75, 5 years long survival is predicted.;EFFECT: high accuracy of the method.
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机译:领域:方法:方法包括确定肿瘤活检物中的浸润深度,癌细胞分化程度,用硝酸银溶液对活检物中的染料进行染色,确定彼此相邻的100个核中核仁M n Sub>的平均数SD ag Sub>核仁中纯银颗粒的含量和标准偏差。在任何浸润深度下没有癌症进展的5年生存率的计算公式为S = 2.289 * M n Sub> + 0.219 * SD ag Sub> + 0.998 * pT-0.102 * G,其中pT是膀胱癌细胞的浸润深度(pT a Sub> = 1,pT 1 Sub> = 2,pT 2 Sub> = 3,pT 3 Sub> = 4,pT 4 Sub> = 5); G是膀胱癌细胞的分化程度(G 1 Sub> = 1,G 2 Sub> = 2,G 3 Sub> = 3)。 S值为& 6.95,可以预测5年生存时间而没有癌症进展。另外确定了核仁中核仁的分布变异系数CV n Sub>和亲银颗粒的分布过量E ag Sub>。没有癌症进展的5年生存期S pr Sub> = 0.1727 * CV n Sub> + 0.3276 * E ag Sub>。 S pr Sub>值> 7.75,可预测5年生存。效果:该方法的准确性高。
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