Mixing with the mixed reaction medicine and the alkylation mannered null manganese reaction

摘要

PROBLEM TO BE SOLVED: To provide a mixed reactant which widens the reactivity of a manganese reactant and is stable, and to provide an alkylation method using the mixed reactant.;SOLUTION: This mixed reactant comprises a mixture obtained by mixing a manganese reactant (for example, tributylmanganese magnesium bromide) and a Lewis acid (for example, boron trifluoride-diethyl ether). The reactant can be used to alkylate (for example, butylate) an acetal compound (for example, 3-phenylpropionaldehyde dimethyl acetal).;COPYRIGHT: (C)2005,JPO&NCIPI