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Calcium phosphate cements and methods for using the same

机译:磷酸钙水泥及其使用方法

摘要

Methods and compositions for producing flowable compositions, e.g. pastes, that set into calcium phosphate products are provided. In the subject methods, dry reactants that include a calcium source and a phosphate source are combined with a setting fluid to produce the flowable composition. A feature of the subject methods is that the dry reactants include a particulate calcium and/or phosphate reactant having a mean particle size of less than about 8 μm and narrow size distribution. Also provided are the compositions themselves as well as kits for use in practicing the subject methods. The subject methods and compositions produced thereby find use in a variety of applications, including the repair of hard tissue defects, e.g., bone defects.
机译:生产可流动组合物的方法和组合物,例如提供了凝固成磷酸钙产品的糊状物。在本主题方法中,将包括钙源和磷酸盐源的干反应物与固化液混合以产生可流动的组合物。本发明方法的特征在于,干反应物包括平均粒径小于约8μm且粒度分布窄的颗粒状钙和/或磷酸盐反应物。还提供了组合物本身以及用于实施本主题方法的试剂盒。由此产生的主题方法和组合物可用于多种应用,包括修复硬组织缺损,例如骨缺损。

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