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Substituted thieno- and thiazolo- 2,3-dpyrimidines and 2,3-cpyridines as inhibitors of tie2

机译:替代thieno-和thiazolo- [2,3-d]嘧啶和[2,3-c]吡啶作为tie2抑制剂

摘要

A compound of the formula(I); wherein the substituents are as defined in the text for use in the production of an anti-angiogenic effect in a warm blooded animal such as man. The compounds are inhibitors Tie2 receptor tyrosine kinase (TEK). embedded image
机译:式(I)化合物;其中取代基如文中所定义,用于在温血动物如人中产生抗血管生成作用。这些化合物是抑制剂Tie2受体酪氨酸激酶(TEK)。 <图像alt =“嵌入式图像” file =“ US20070135455A1-20070614-C00001.GIF” he =“ 41.57mm” imgContent =“ chem” imgFormat =“ GIF” wi =“ 71.12mm“ />

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