Anti-abnormal type prion monoclonal antibody, process for producing the same, and immunoassay of abnormal type prion protein using the same

摘要

A monoclonal antibody which recognizes abnormal type prion protein alone is disclosed. By the present invention, an anti-abnormal type prion monoclonal antibody whose corresponding antigen is an abnormal type prion protein, and which does not substantially react with normal type prion protein was first provided. Since the corresponding antigen of the monoclonal antibody according to the present invention is the naturally occurring abnormal type prion protein, measurement of the abnormal type prion protein may be attained with high sensitivity.