首页>
外国专利>
Interventions to mimic the effects of calorie restriction
Interventions to mimic the effects of calorie restriction
展开▼
机译:模拟热量限制的干预措施
展开▼
页面导航
摘要
著录项
相似文献
摘要
Long term calorie restriction has the benefit of increasing life span. Methods to screen interventions that mimic the effects of calorie restriction are disclosed. Extensive analysis of genes for which expression is statistically different between control and calorie restricted animals has demonstrated that specific genes are preferentially expressed during calorie restriction. Screening for interventions which produce the same expression profile will provide interventions that increase life span. In a further aspect, it has been discovered that test animals on a calorie restricted diet for a relatively short time have a similar gene expression profile to test animals which have been on a long term calorie restricted diet.
展开▼