A method for producing a Pharmaceutical composition for the Diclofenac Sodium dual release

摘要

This refers to a process for producing a Pharmaceutical composition for Diclofenac Sodium dual release.This relates in particular to a method for producing a Pharmaceutical composition for Diclofenac Sodium dual Release containing a total of between 100 and 150 mg of Diclofenac Sodium Nuclei divided in 2 of them, the first and the second internal external, containing the first and The HPMC,Where to get the free composition in artificial intestinal Juice between 20% and 40% of its content of Diclofenac in the first 30 minutes, adding a Predetermined amount of Isopropyl alcohol to the inner core during the granulation process and then dried gr Reversed in a fluidized bed.