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Use of a beta agonist for Treatment of Kidney and gallbladder disorders in patients with Spinal Cord Injury

机译:使用β激动剂治疗脊髓损伤患者的肾脏和胆囊疾病

摘要

Refers to the use of beta 3 adrenergic receptor agonists for the Prevention and Treatment of renal lesions and / or Functional disorders of vesicular lesions, in particular of the Neurogenic bladder of origin as a result of spinal cord injury.Claim 1: Use of beta 3 adrenergic receptor agonist, possibly in the form of a pharmaceutically Active Salt thereof for the preparation of a Medicament for the prophylaxis and / or treatment of renal lesions and renal diseases as a result of high pressure Tap Ologicas or High pressures in the bladder detrusor function of an erroneous result.Claim 2: Use of a Beta 3 adrenergic receptor agonist, possibly in the form of a pharmaceutically Active Salt thereof for the preparation of a Medicament for the treatment of Diseases of the bladder as a result of injury to the spinal cord.Use according to claim 5: one of claims 1 to 4, wherein the beta 3 adrenergic receptor agonist is a compound according to formula (1) with X = h, CL, BR, i), y = h, CL, BR, I, r = Oh, Methyl, methoxy ethoxy, or a pharmaceutically acceptable Salt of the M ISM.Claim 17: Method for the Treatment or prophylaxis of renal lesions and renal diseases as a result of high pressure or High pressures in Pathological Bladder, detrusor function resulting from an incorrect which is used in medicine as a The preceding claims.Claim 1: Method for the treatment of Bladder Diseases as a result of a Spinal Cord Injury, Diseases of the bladder as a result of Parkinson's disease, Alzheimer's disease, a brain injury or trauma, multiple sclerosis, In a drug that is used in one of the preceding claims.
机译:指使用β3肾上腺素能受体激动剂预防和治疗肾损伤和/或水泡性损伤,特别是由于脊髓损伤导致的神经源性膀胱的功能性疾病。索赔1:使用β 3肾上腺素能受体激动剂,可能是其药物活性盐的形式,用于制备预防和/或治疗由于高压Tap Ologicas或膀胱逼尿肌高压导致的肾脏病变和肾脏疾病的药物要求2:β3肾上腺素能受体激动剂,可能以其药物活性盐的形式用于制备治疗因脊髓损伤而引起的膀胱疾病的药物6.根据权利要求5的用途:权利要求1至4之一,其中所述β3肾上腺素能受体激动剂是根据式(1)的化合物,其中X = h,CL,BR,i),y = h,CL,BR , 一世,r = Oh,甲基,甲氧基乙氧基或M ISM的药学上可接受的盐。权利要求17:用于治疗或预防由于病理性膀胱的高压或高压,逼尿肌功能引起的肾脏病变和肾脏疾病的方法1.治疗因脊髓损伤引起的膀胱疾病,因帕金森氏病引起的膀胱疾病,阿尔茨海默氏病,脑的方法在前述权利要求之一中使用的药物中,损伤或外伤,多发性硬化。

著录项

  • 公开/公告号AR056552A1

    专利类型

  • 公开/公告日2007-10-10

    原文格式PDF

  • 申请/专利权人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH;

    申请/专利号AR2006P104298

  • 发明设计人 MARTIN C. MICHEL;

    申请日2006-09-29

  • 分类号A61K31/192;A61K31/216;A61P13/10;A61P13/12;

  • 国家 AR

  • 入库时间 2022-08-21 20:59:35

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