method and apparatus for substantially isolating cardiac circulation from systemic circulation apparatus for perfusing the heart with a therapeutic agent, obstruction catheter for obstructing flow between a main vessel and one or more branched vessels, method for administering a therapeutic agent to the heart and support structure percutaneously manageable to maintain coronary sinus patency

摘要

"METHOD AND APPARATUS FOR SUBSTANTIALLY INSULATING HEART SYSTEM CIRCULATION, APPARATUS FOR PERFECTING THE HEART WITH A THERAPEUTIC AGENT, OBSTRUCTION CATHETHER FOR OBSTRUCTING EASTER VASTUS EASTER CURRENT In a method to substantially isolate the cardiac circulation from the systemic circulation (300), the flow between the coronary sinus and the right atrium is obstructed (202). A venous collection device having a collection lumen and support structure is located in the coronary sinus (304). The support structure is used to maintain coronary sinus patency during the collection of fluid through the collection lumen (206). An artificial flow path is used to maintain coronary sinus patency during fluid collection through the collection lumen (206). An artificial flow path is provided between the collection lumen and one or more coronary arteries, thus isolating the cardiac circulation (208). According to the method, cardiac pumping to systemic circulation can be maintained during isolation of the cardiac circulation.