11beta long chain substituted estratrienes, process for their preparation, pharmaceutical preparations containing these 11beta long chain substituted estratrienes and their use in the manufacture of pharmaceuticals

摘要

This invention describes a 11beta-long-chain-substituted estratriene of general formula (I), in which R11 is a long-chain radical that has a nitrogen atom and optionally a sulfur atom, which in addition can be functionalized in the terminal position with a perfluoroalkyl group or an optionally substituted arly radical. The compound can have antiestrogenic or tissue-selective estrogenic properties and be suitable for the production of pharmaceutical agents.