COMBINED USE OF ANTITUMOR INDOLOPYRROLOCARBAZOLE DERIVATIVE AND OTHER ANTITUMOR AGENT

摘要

A combination of pharmaceutical preparations which are simultaneously, separately, or successively administered in treatments for cancers. It comprises the following two separate preparations: * a pharmaceutical preparation comprising a pharmaceutically acceptable support or diluent and either at least one compound represented by the general formula ???? ??? (wherein R1 and R2 each independently represents hydrogen, lower alkyl, etc.; G represents a pentose group, etc.; and X1 and X2 each independently represents hydrogen, halogeno, etc.) or a pharmaceutically acceptable salt of the compound and * a pharmaceutical preparation comprising a pharmaceutically acceptable support or diluent and any of an anticancer alkylating agent, anticancer antimetabilite, anticancer antibiotic, plant-derived anticancer agent, and the like (the pharmaceutical preparation containing at least one compound represented by the above formula ??? or a pharmaceutically acceptable salt thereof may be used in combination with two or more other anticancer agents). Also provided is a method of treatments for cancers, characterized by administering these pharmaceutical preparations in combination.