BIO-SPECIFIC ANTIBODY TO TREAT THE LYMPHYCUS B-LYMPHOMA AND CELL LINE.

摘要

THE INVENTION DESCRIBES BISPECIFIC ANTIBODIES WITH SELECTIVE CYTOTOXIC ACTIVITY AGAINST MALIGNAS B CELLS. THE BIESPECIFIC ANTIBODIES JOIN AN ANTIGEN OF AN EFFECTIVE CELL AND A HETERODYMERIC PROTEIN OF 28/32 KDA OF THE SURFACE OF THE MALIGINE B CELL. THE INVENTION INCLUDES ALSO THE MONOSPECIFIC COMPONENTS OF THE BIESPECIFIC ANTIBODIES, THE HUMANIZED VERSIONS OF THE SAME, AND THE HUMANIZED BISPECIFIC ANTIBODIES. THE INVENTION ALSO DESCRIBES THERAPEUTIC AND DIAGNOSTIC METHODS USED BY THESE ANTIBODIES.