首页> 外国专利> NEW N-ACYLATED 4-HYDROXYPHENYLAMINE DERIVATIVES WITH ANALGESIC PROPERTIES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

NEW N-ACYLATED 4-HYDROXYPHENYLAMINE DERIVATIVES WITH ANALGESIC PROPERTIES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

机译:具有止痛特性和包含它们的药物成分的新的N-乙酰化的4-羟苯胺衍生物

摘要

The presentinvention relates to aseries of new N-acylated4-hydroxyphenylaminederivatives, linked viaan alkylene bridge tothe nitrogen atom of al,2-benzisothiazol-3(2H)-one1,1-dioxide group, of formula(I), in which n is a numberfrom I to 5, and to processesfor preparing these derivativesand to pharmaceuticalcompositions containing said derivatives; these compounds possess highanalgesic activity free from antipyretic activity, and they displaylittle hepatotoxic effect.
机译:现在本发明涉及系列新的N-酰化4-羟苯胺衍生产品,通过亚烷基桥a的氮原子l,2-苯并噻唑-3(2H)-一分子式为1,1-二氧化物的基团(I),其中n是一个数字从我到5,再到过程用于制备这些衍生物和制药含有所述衍生物的组合物;这些化合物具有很高的无解热活性的止痛药,它们表现出肝毒性作用小。

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