SHUTTLE VECTOR AND USE IN EVALUATION OF MUTATION PHENOMENON

摘要

the present invention relates to a dna vector construction, such as ashuttle, useful in methods for the detection and / or quantitative evaluationorquality of a phenomenon of transfer, such as onessomatic hypermutation in the midst of a, of a cell or a group ofthe cells.the shuttle vector is useful in a method of diagnosis and / orprognosis of hematological disease evolution.