METHOD OF ISOLATING STEM CELLS AND IDENTIFYING DIFFERENTIALLY EXPRESSED GENES IN SONIC HEDGEHOG EXPRESSING CELLS AND DESCENDENT CELLS

摘要

The invention provides for methods of isolating stem cells and their descendant cells, as well as identifying genes that are differentially expressed in Sonic Hedgehog (Shh) gene expressing cells. More particularly, the present invention relates to methods for discovering genes and proteins that may be useful in tissue engineering, regeneration, reconstruction and/or repair of tissues that are actively, or have at any time during the life of the organism, expressed the Sonic Hedgehog gene.