ANTITUMOR COMBINATION OF 3-AMINO-1,2,4-BENZOTRIAZINE 1,4-DIOXIDE / PACLITAXEL / PLATINUM
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机译:3-氨基-1,2,4-苯并三嗪1,4-二氧化物/多效胺/铂的反组合
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摘要
In accordance with the present invention there is provided a method of treating a mammal having a solid tumor, the method comprising: a) administering to the mammal an effective amount of 3-amino-1,2,4-benzotriazine 1,4-dioxide; b) administering to the mammal an effective amount of paclitaxel; and c) administering to the mammal an effective amount of a platinum complex. The method provides unexpected synergistic efficacy. The invention further provides a kit for treatment of a mammalian tumor comprising 3-amino-1,2,-benzotriazine 1,4-dioxide, paclitaxel and a platinum complex.
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