首页> 外国专利> USE OF GENE WHICH VARIES IN AMOUNT OF EXPRESSION DURING COURSE OF MALIGNANT TRANSITION FROM PRECANCER TO CANCER

USE OF GENE WHICH VARIES IN AMOUNT OF EXPRESSION DURING COURSE OF MALIGNANT TRANSITION FROM PRECANCER TO CANCER

机译:从恶性肿瘤向恶性肿瘤转移过程中各种表达量基因的表达

摘要

PPROBLEM TO BE SOLVED: To provide the use of a gene for diagnostic methods and diagnostic agents for cancer, screening methods for therapeutic drugs, therapeutic vectors and therapeutic methods on the basis of analyzing a great number of genes and finding a gene exhibiting specific expression in the state of cancer and precancer. PSOLUTION: Disclosed are a diagnostic method for cancer including a process of testing the expression amount of a gene taking a specific DNA as cDNA, a diagnostic method featured by searching the change of expression amount of a polypeptide encoded by the gene, a diagnostic method featured by searching the expression amount of the gene mRNA, a diagnostic agent for cancer, a screening method for samples having anticancer activity, a method for producing a medicinal composition having anticancer activity, and a therapeutic method. PCOPYRIGHT: (C)2009,JPO&INPIT
机译:

要解决的问题:在分析大量基因并发现具有以下特征的基因的基础上,提供一种基因用于癌症的诊断方法和诊断剂,治疗药物的筛选方法,治疗载体和治疗方法的用途在癌症和癌前状态中的特异性表达。

解决方案:公开了一种用于癌症的诊断方法,包括测试以特定DNA为cDNA的基因的表达量的过程,该诊断方法的特征在于搜索该基因编码的多肽的表达量的变化。通过搜索基因mRNA的表达量来进行诊断的方法,癌症的诊断剂,具有抗癌活性的样品的筛选方法,具有抗癌活性的药物组合物的制造方法以及治疗方法。

版权:(C)2009,日本特许厅&INPIT

著录项

  • 公开/公告号JP2008259424A

    专利类型

  • 公开/公告日2008-10-30

    原文格式PDF

  • 申请/专利权人 ISHIHARA SANGYO KAISHA LTD;

    申请/专利号JP20050227975

  • 发明设计人 KONDO NOBUO;ISHIKAWA TOSHIO;

    申请日2005-08-05

  • 分类号C12N15/09;C12Q1/68;C12N1/15;C12N1/19;C12N1/21;C12N5/10;G01N33/53;G01N33/574;A61K45;A61P35;A61P1/02;A61K48;A61K31/7088;A61K35/76;A61K35/12;C12Q1/02;

  • 国家 JP

  • 入库时间 2022-08-21 20:24:05

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号