NEW GENE BRACHYURY EXPRESSION BY NUCLEAR INHIBITOR, BENI REGULATING DEVELOPMENT OF MESODERM IN EARLY DEVELOPMENT OF VERTEBRATE

摘要

PPROBLEM TO BE SOLVED: To provide a gene responding to activin A in early development. PSOLUTION: The inventor investigated the embryo of Xenopus by using exhaustive microarray method and find out a Unigene code XI. 7756 (named as BENI, Brachyury Expression by Nuclear Inhibitor) as a gene responding to activin A in early development and greatly reducing its expression, and that the gene regulates induction of differentiation of mesoderm while regulating expression of Brachyury which is a specific factor of mesoderm in the nucleus. PCOPYRIGHT: (C)2008,JPO&INPIT