Method for purifying 11β-21-dihydroxy-2'-methyl-5'βH-pregna-1,4-dieno 17,16-D oxazole-3,20-dione

摘要

Process for preparing the compound 11beta-21-dihydroxy-2'-methyl-5'betaH-pregna-1,4-dieno[17,16-d]oxazoline-3,20-dione of formula (I):which comprises adsorbing said compound, contained into an aqueous solution resulting from fermentation broths or process streams, on an adsorbent polymeric resin having a styrenic or acrylic matrix and subsequently desorbing the said compound by eluting the resin with suitable mixture of water with a water-miscible organic solvent.