A method for producing vesicles, vesicles obtained by this manufacturing method, a manufacturing method of the frozen particles used in the production of vesicles

摘要

While controlling the desired properties such as particle size present invention relates, is to provide a method for producing a vesicle can be achieved with high encapsulation efficiency of the desired material. Create a W / O emulsion and an aqueous solution containing in suspension or dissolved substances which [SOLUTION] encapsulated, the oil phase containing an emulsifier, then the oil phase liquid solution of the W / O emulsion is a frozen particles was replaced vesicle constituent lipid emulsifier frozen particle surface by removing the oil phase is cooled to a temperature that maintains the state of, and thereafter to add the oil phase containing a vesicle constituent lipids in the frozen particles and stirred , and was added to the external aqueous phase frozen particles whose surface is covered by a lipid membrane and hydrate the lipid film and the external water phase. [Selection] Figure Figure 1