Transcription factor Nrf2 activator and food provided with the function

摘要

The composition, Nrf2 activator and food according to the present invention comprise isohumulones or isomerized hop extract as an active ingredient. They are useful for the treatment, prevention or amelioration of diseases or conditions that can be treated, prevented or ameliorated by activation of the transcription factor Nrf2. More specifically, the composition, Nrf2 activator and food according to the present invention are chronic diseases (for example, arteriosclerosis, hypertension, diabetes mellitus) that are thought to develop or progress due to oxidative stress in the living body or cell damage due to environmental substances. , Cranial neurodegenerative diseases, skin diseases, eye diseases, asthma, cancer, etc.), and are useful for detoxification of xenobiotics.