In vitro evaluation method of the immune response modifying activity

摘要

The present invention, a method that can be performed in vitro, to evaluate and cheaply, efficiently and accurately in a short period of time, the immune response modifying activity that specific chemical substances such as environmental materials has, the Th1 / Th2 adjuvant activity in particular and an object thereof is to provide. Therefore, by stimulating a specific material immature dendritic cells, and to analyze the mature dendritic cells induced to differentiate from the immature dendritic cells by the stimulus, the method for evaluating the immune response modifying activity of the specific substance has I provide. Also provided is a volatile sterilization method using an organic solvent as a poorly water-soluble substance preparation method for stimulating immature dendritic cells with a poorly water-soluble substance of the specific substance.