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Drug safety test system and drug safety testing method
Drug safety test system and drug safety testing method
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机译:药品安全性测试系统及药品安全性测试方法
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摘要
Measurement conditions that mimic the biological environment, and an object thereof is to provide reliability of risk assessment of pharmaceuticals is high, the system and Good Laboratory Method. A Good Laboratory method of using a sensor that is used consists cells homologue thereof HERG and ion channels, with a plurality of measuring electrodes, Good Laboratory methods of the present invention, the A) under study medication After the step of measuring the electrical response of the sensor in a state of contact with a sample solution containing step of measuring the electrical response of the sensor in a state of contact with the control solution which does not contain, and B) the tested drugs, in step C) B1 includes the step of measuring the electrical response of the sensor in a state of contact with the control solution which does not contain the tested drugs again, compares the voltage signal measured at the step C and the step A, and based on the results of Te, I to determine the risk of the study medication.
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