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Small Peptides And Methods For Inhibiting The Infiltration Of Eosinophils Into Airways

机译:小肽和抑制嗜酸性粒细胞渗入气道的方法

摘要

Methods for treating cutaneous inflammation, are described. Also described is a method for inhibiting the mucous release into airways of a patient, a method for blocking IgE activation of a lymphocyte, a method for stabilizing the cell membrane of a lymphocyte, thereby preventing their further involvement in the increased inflammatory response to an IgE antigen challenge, and a method for inhibiting the migration of T-cells. Such methods involve administering to said patient a therapeutically effective amount of a peptide having the formula f-Met-Leu-X, wherein X is selected from the group consisting of Tyr, Tyr-Phe, Phe-Phe and Phe-Tyr.
机译:描述了治疗皮肤炎症的方法。还描述了一种抑制粘液释放到患者气道中的方法,一种阻止淋巴细胞的IgE活化的方法,一种稳定淋巴细胞的细胞膜,从而防止它们进一步参与对IgE的炎性反应增加的方法。抗原攻击,以及抑制T细胞迁移的方法。此类方法包括向所述患者施用治疗有效量的具有式f-Met-Leu-X的肽,其中X选自Tyr,Tyr-Phe,Phe-Phe和Phe-Tyr。

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